Original Article – Page 3 – Asian Pacific Journal of Allergy and Immunology

April 8, 2024

Pulmonary function characteristics in childrenwith suspected asthma: implications for asthma diagnosis

In children suspected of asthma, diagnosis is confirmed via variable expiratory airflow limitation. However, there is no single gold standard test for diagnosing asthma.

Asthma, Children, diagnosis, paediatric, spirometry

April 8, 2024

Serum levels of specific IgE to cow’s milk and its components as predictors of anaphylaxis in Chinese childrenwith cow’s milk allergy

Cow’s milk allergy (CMA) is one of the most common food allergies in young children. As improved diagnostic tools, allergic tests are inconsistent and limited in predicting anaphylaxis.

Anaphylaxis, Casein, IgE-mediated cow’s milk allergy, Specific IgE, specificity

April 8, 2024

Treatment difficulties in wheat oral immunotherapyand the predictive value of wheat-specific IgE

Factors associated with wheat oral immunotherapy (OIT) difficulties in patients with IgE-mediated wheat allergy have not been well studied.

Anaphylaxis, food allergy, IgE-mediated, oral immunotherapy, Wheat

January 14, 2024

The prevalence of IgE positivity, environmental factors,and clinical implications associated with mite speciesin allergic patients in Taiwan

Allergic diseases are a growing public health concern with increasing prevalence and severity. Allergens play significant roles in triggering immune responses and the development of allergic reactions.

allergic dermatitis, basophil activation, Cheyletus eruditus, mite allergy, mite specific IgE, Predatory mite

January 14, 2024

Evaluation of adherence and attitudes of patientswith allergic rhinitis to nasal steroid treatment

Allergic rhinitis (AR) is defined as an inflammatory disease of the nose. Nasal corticosteroids (NCS) are one of the most effective drugs used in AR treatment.

Adherence, Allergic rhinitis, medication, Morisky scale

January 14, 2024

A new pepper allergen Zan b 1.01 of 2S albumins:Identification, cloning, characterization, and cross-reactivity

Zanthoxylum bungeanum (Sichuan pepper; 花椒 in Chinese) is used as a spice worldwide and is a potentially life-threatening allergenic food source, as first reported by our team in 2005. However, its allergen components are unknown.

2S albumin, cashew seed, citrus allergy, pepper allergy, Zan b 1.01, Zanthoxylum bungeanum Maxim, α-amylase inhibitor

January 14, 2024

Production of anti-human cannabinoid receptor 2 (CB2) monoclonal antibody using non-viral vectorinduced human CB2 expressing myeloma as an immunogen

Cannabinoid receptor 2 (CB2) of the cannabinoid system is predominantly expressed on immune cells and involved in a diverse range of immune functions. However, the role of CB2 in immunoregulation is still controversial. One of the challenges in the detailed characterization and functional study of CB2 is the lack of CB2-specific monoclonal antibodies (mAbs).

Anti-cannabinoid receptor 2 antibody, Cannabinoid receptor, Cannabinoid system, Monoclonal antibody production, Non-viral vector expression system

January 14, 2024

Anaphylaxis in children: Effect of age and atopic status

Anaphylaxis is a life-threatening allergic reaction with rising incidence worldwide. Young children’s limited ability to express symptoms adds unique diagnostic challenges.

adrenaline, Anaphylaxis, atopy, Children, young

January 14, 2024

Differences in asthma-related outcomesby anti-IL-5 biologics, omalizumab, and dupilumabbased on blood eosinophil counts

Selecting optimal biologics based on type 2 biomarkers has been of interest in severe asthma treatment. However, few direct biomarker stratification-based comparisons have been made.

asthma biologics, eosinophil, IL-5, Severe asthma

January 14, 2024

Responses of primary human nasal epithelial cellsto COVID-19 vaccine candidate

Upper respiratory tract is the primary target of SARS-CoV-2. Therefore, nasal immune responses act as the first line of defense against SARS-CoV-2 infection.

COVID-19 vaccine, delivery systems, primary human nasal epithelial cells, RBD, SARS-CoV-2