Treatment difficulties in wheat oral immunotherapyand the predictive value of wheat-specific IgE
Factors associated with wheat oral immunotherapy (OIT) difficulties in patients with IgE-mediated wheat allergy have not been well studied.
The prevalence of IgE positivity, environmental factors,and clinical implications associated with mite speciesin allergic patients in Taiwan
Allergic diseases are a growing public health concern with increasing prevalence and severity. Allergens play significant roles in triggering immune responses and the development of allergic reactions.
Evaluation of adherence and attitudes of patientswith allergic rhinitis to nasal steroid treatment
Allergic rhinitis (AR) is defined as an inflammatory disease of the nose. Nasal corticosteroids (NCS) are one of the most effective drugs used in AR treatment.
A new pepper allergen Zan b 1.01 of 2S albumins:Identification, cloning, characterization, and cross-reactivity
Zanthoxylum bungeanum (Sichuan pepper; 花椒 in Chinese) is used as a spice worldwide and is a potentially life-threatening allergenic food source, as first reported by our team in 2005. However, its allergen components are unknown.
Production of anti-human cannabinoid receptor 2 (CB2) monoclonal antibody using non-viral vectorinduced human CB2 expressing myeloma as an immunogen
Cannabinoid receptor 2 (CB2) of the cannabinoid system is predominantly expressed on immune cells and involved in a diverse range of immune functions. However, the role of CB2 in immunoregulation is still controversial. One of the challenges in the detailed characterization and functional study of CB2 is the lack of CB2-specific monoclonal antibodies (mAbs).
Anaphylaxis in children: Effect of age and atopic status
Anaphylaxis is a life-threatening allergic reaction with rising incidence worldwide. Young children’s limited ability to express symptoms adds unique diagnostic challenges.
Differences in asthma-related outcomesby anti-IL-5 biologics, omalizumab, and dupilumabbased on blood eosinophil counts
Selecting optimal biologics based on type 2 biomarkers has been of interest in severe asthma treatment. However, few direct biomarker stratification-based comparisons have been made.
Responses of primary human nasal epithelial cellsto COVID-19 vaccine candidate
Upper respiratory tract is the primary target of SARS-CoV-2. Therefore, nasal immune responses act as the first line of defense against SARS-CoV-2 infection.
Atmospheric environment and persistence of pediatricasthma: A population-based cohort study
Asthma is a heterogeneous disease with different outcomes. For children with asthma at the age of 7 years, 67–75% are symptom-free as adults. Data on the important link between childhood and adult asthma are sparse.
Factor associated with food allergy among preschool children with atopic dermatitis, and resolution of atopic dermatitis
Food allergy (FA) has been reported in one-third of children with moderate-to-severe atopic dermatitis (AD).