Original Article – Page 5 – Asian Pacific Journal of Allergy and Immunology

April 23, 2023

Efficacy and safety of low- and high-dose slow oral egg immunotherapy for hen’s egg allergy: Single-center non-inferiority randomized trial

Low-dose oral immunotherapy (OIT) is a safe treatment for hen’s egg allergy; however, comparison of its therapeutic effects with those of high-dose OIT has not been reported.

efficacy, Egg allergy, oral immunotherapy, safety

April 23, 2023

Safety of House Dust Mite Subcutaneous Immunotherapy with a rush and cluster combination protocol in the build-up phase

Conventional and cluster subcutaneous immunotherapy (SCIT) are effective but may be time-consuming. Rush SCIT may offer a more convenient treatment option to patients and be of shorter duration; however, it is also associated with a higher incidence of systemic adverse reactions. Therefore, a combination of protocols between rush and cluster SCIT could have a superior risk-benefit ratio.

allergen, house dust mites, Immunotherapy, risk factor, safety

April 23, 2023

The natural history of childhood-onset nonallergic rhinitis; a long-term follow-up study

Non-allergic rhinitis (NAR) is characterized by symptoms of nasal inflammation without allergic sensitization. The long-term outcome of NAR in children is poorly defined.

Allergic rhinitis, childhood-onset nonallergic rhinitis, Children, natural history, nonallergic rhinitis, Sensitization

April 23, 2023

Mucosal brushings for nasal specific IgE to predict house dust mite driven allergic rhinitis

Skin prick testing and serological identification of allergen specific immunoglobulin E (spIgE) are standard tests for allergic rhinitis but can only identify systemic responses. In contrast, nasal allergen challenge (NAC), directly assess localized nasal mucosal reactivity, but is time consuming. Identification of spIgE from nasal brushings (nasal spIgE) is an alternative technique.

Allergic rhinitis, house dust mite, local allergic rhinitis, nasal allergen challenge, nasal brushings, nasal specific IgE, non allergic rhinitis

April 23, 2023

The use of topical nasal steroids to improve continuous positive airway pressure compliance in patients with obstructive sleep apnea: An updated systematic review and meta-analysis of randomized control trials

Nasal steroids are commonly prescribed to reduce nasal side effects, which are the primary cause of continuous positive airway pressure (CPAP) intolerance in obstructive sleep apnea (OSA) patients.

Continuous positive airway pressure, Nasal steroid, obstructive sleep apnea, steroid

February 12, 2023

Children with wheat anaphylaxis and with low wheat specific IgE have a different IgE immunoblot pattern than those with high wheat specific IgE

Children with wheat anaphylaxis can present with a wide range of wheat-specific IgE (sIgE).

Anaphylaxis, Food hypersensitivity, Gliadin, immunoblotting, wheat hypersensitivity

February 12, 2023

IgE-mediated fish allergy in Singaporean children

Fish is one of the common causes of food allergy and there is limited literature about fish allergy in Singapore.

Anaphylaxis, fish allergy, IgE-mediated food allergy, natural history, Singaporean children

February 12, 2023

Skin prick test and serum specific IgE in predicting dust mite-induced allergic rhinitis diagnosed from nasal provocation test in chronic rhinitis children

Allergen skin prick test (SPT) and serum specific immunoglobulin E (sIgE) are effective diagnostic tests in allergic rhinitis (AR), however, positive results may not always correlate with clinical allergies. A nasal provocation test (NPT) can identify the causative allergen for immunotherapy, but it’s not routinely performed.

house dust mite, nasal provocation test, Serum specific IgE, Skin prick test

February 12, 2023

Perioperative immediate hypersensitivity incidence,clinical characteristics, and outcomesafter allergological evaluation: A multi-disciplinary protocol from tertiary hospital, Thailand

Perioperative immediate hypersensitivity reaction (POH) is an immediate hypersensitivity reaction during an anesthesiologist monitored procedure. We report data of clinically-suspected POH (csPOH) patients undergoing an allergist-performed unified diagnostic workup algorithm for POH.

Allergy, Anaphylaxis, anesthesia, Chlorhexidine, drug allergy, investigation, latex, perioperative hypersensitivity

February 12, 2023

Humoral and cellular immune responses against SARS-CoV-2 variants of concern induced by heterologous CoronaVac/ChAdOx-1 versus homologous ChAdOx-1 vaccination in the elderly

The concept of heterologous vaccination against SARS-CoV-2 infection has been adopted in Thailand with limited data on the induction of humoral and cellular immunity, particularly the CoronaVac/ChAdOx-1 (CoVac/ChAd) regimen in the elderly.

COVID-19 vaccine, Elderly, Heterologous vaccination, Homologous vaccination