Original Article – Page 15 – Asian Pacific Journal of Allergy and Immunology

October 26, 2020

Overall survival and prognostic factors in diabetic patients with invasive fungal rhinosinusitis

Patients with diabetes mellitus (DM) are susceptible to invasive fungal rhinosinusitis (IFRS). The mortality rate of IFRS varies greatly among the patients with DM.

cavernous sinus, diabetes mellitus, fungal, rhinosinusitis, risk factors

October 26, 2020

GWAS-identified variants to allergic disease and early environmental exposure in Chinese schoolchildren with allergic rhinitis induced by house dust mite

There is growing evidence that environmental exposure in early life is associated with the development of childhood allergic rhinitis.

Allergic rhinitis, Children, early environment, house dust mite, variants

September 13, 2020

High fetal bisphenol A exposure enhances IL22 secretion: A proinflammatory cytokine

Bisphenol A (BPA) is an industrial product, widely used in human consumed types of equipment that can be transmitted orally, by inhalation or through dermal absorption and is detectable in many body fluids including cord blood. A correlation between BPA concentration in maternal serum and cord blood has been demonstrated previously, suggesting a possible transfer of BPA via the transplacental path.

Cord blood, cytokines, Interleukin 22, maternal exposure, newborn

September 13, 2020

Characteristics of immediate hypersensitivity reaction to paclitaxel-based chemotherapy in gynecologic cancer patients

Immediate hypersensitivity reactions (IHRs) are commonly found in patients receiving paclitaxel. Effects of paclitaxel vary because of variable co-therapy or re-challenge with paclitaxel.

adverse drug reactions, hypersensitivity, malignancy, paclitaxel, risk factors

September 13, 2020

Regulatory T cell and cytokine changes in children undergoing 3 days rush venom immunotherapy

Rush venom immunotherapy (VIT) is the recommended treatment for patients with Hymenoptera anaphylaxis. Specific data regarding regulatory T cell and cytokine changes in children receiving rush VIT are sparse.

Anaphylaxis, Children, cytokines, Hymenoptera, regulatory T cells, subcutaneous immunotherapy

September 9, 2020

Toll-like receptor 2-mediated induction of human beta-defensin 2 expression by Leptospira interrogans in human kidney cells

Leptospirosis is a zoonotic disease caused by Leptospira interrogans. Severe leptospirosis is often accompanied by kidney dysfunction caused by chronic infection. The kidney pathology involves bacterial invasion and inflammation caused by pro-inflammatory cytokines. Human beta defensins (hBDs) are antimicrobial peptides induced by microbial infection and/or pro-inflammatory cytokines. One function of hBDs is the recruitment of immune cells that leads to inflammation. However, the expression of hBDs by kidney epithelium in response to pathogenic Leptospira has never been investigated.

human beta-defensins, kidney epithelium, Leptospira, leptospirosis, TLR2

September 9, 2020

Does Trimethoprim-Sulfamethoxazole prophylaxis induce myelosuppression in primary immune deficiency disease patients; A retrospective, 3 groups comparative study

The possible myelosuppression side effect of Trimethoprim-Sulfamethoxazole (TMP-SMX) on primary immune deficiency (PID) patients has not been established yet.

myelosuppression, Neutropenia, primary immune deficiency, prophylaxis, TMP-SMX

September 9, 2020

A double-blinded, randomized, split-side, vehicle-controlled study of the efficacy of cleanser containing Acanthus ebracteatus Vahl., Suregada multiflora, and Acacia concinna in patients with atopic dermatitis: A pilot study

Barrier repair therapy is the key management approach for both eczematous and non-lesional skin of atopic dermatitis. The use of appropriate cleansers to enhance skin hydration is an adjunctive treatment that increases topical drug penetration. Anti-inflammatory properties of various medicinal plants in tropical Asia have been reported.

adjunctive therapy, atopic dermatitis, cleanser, herbal medicine, transepidermal water loss

August 30, 2020

Is mold sensitization associated with severe asthma exacerbation in children?

Mold sensitization has been reported as a factor associated with severe asthma exacerbation (SAE).

Alternaria, asthma exacerbation, Children, mold sensitization, Severe asthma

August 30, 2020

A new index for distinguishing hypereosinophilic syndrome and antineutrophil cytoplasmic antibody-negative eosinophilic granulomatosis with polyangiitis

It is difficult to differentiate between hypereosinophilic syndrome (HES) and antineutrophil cytoplasmic antibody (ANCA)-negative eosinophilic granulomatosis with polyangiitis (EGPA).

differentiation, eosinophilic granulomatosis with polyangiitis, Hypereosinophilic syndrome, index, Predictor