Anxiety and depression in allergic rhinitis patients during COVID-19 pandemic in Wuhan, China
During COVID-19 pandemic, many allergic rhinitis (AR) patients stopped their treatment including pharmacotherapy and allergen immunotherapy.
CD28 confers CD4+ T cells with resistance to cyclosporin A and tacrolimus but to different degrees
Cyclosporin A (CSA) and tacrolimus (TAC) suppress T-cell activation and subsequent proliferation by inhibiting calcineurin. Though they have the same target, CSA and TAC have quite different molecular structures, indicating quantitative and/or qualitative differences in their effects.
Efficacy of drug therapies in antihistamine refractory chronic spontaneous urticaria: Real life data
Omalizumab is a safe and effective treatment for antihistamine-refractory chronic spontaneous urticaria (CSU) but is insufficient in one-third of patients. For serious cases in which omalizumab is ineffective, cyclosporine or methotrexate may be preferred. Most drug trials in CSU have focused on omalizumab or cyclosporine monotherapy.
Depression scores change significantly after omalizumab treatment in patients with chronic spontaneous urticaria
Chronic spontaneous urticaria (CSU) is frequently associated with psychiatric comorbidities.
Effect of fexofenadine/pseudoephedrine combination tablet on nasal obstruction in patients with allergic rhinitis using rhinomanometry: A randomized controlled trial
A fexofenadine/pseudoephedrine combination tablet (F/P) is an optimal product for nasal obstruction. It contains fexofenadine hydrochloride, a histamine H1-receptor antagonist for sneezing and rhinorrhea and pseudoephedrine hydrochloride, an α-adrenergic agonist. The effect of an antihistamine-decongestant on nasal obstruction has been demonstrated in previous studies, but onset of action and efficacy data on nasal obstruction are limited.
Allergic contact dermatitis to topical medicaments: Revisited
Allergic reaction to topical drugs varies depending on use and availability of topical drugs and self-medication.
Social restriction versus herd immunity policies in the early phase of the SARS-CoV-2 pandemic: A mathematical modelling study
Two main strategies to cope with the coronavirus disease 2019 (COVID-19) pandemic—lockdown (social restriction) and non-lockdown (herd immunity plan)—have been implemented in several countries.
Interaction of the TLR4 rs1927911 polymorphism with house dust mite sensitization in allergic rhinitis with its prognosis
Sensitization to the house dust mite (HDM) plays important roles in the development of allergic rhinitis (AR). Toll-like receptor 4 (TLR4) is a key initiator of the innate immune system upon exposure to environmental factors.
Killer cell immunoglobulin-like receptors in Thai patients with multiple myeloma
Natural killer (NK) cells have been implicated in the immune response against multiple myeloma (MM) cells. Killer cell immunoglobulin-like receptors (KIRs) regulate NK cell activity by recognizing specific human leukocyte antigen (HLA) class I as ligands.
The validity and reliability of the Thai version of the asthma control test
The Asthma Control Test (ACT) has been widely used for the assessment of asthma control. However, it has never been validated in adult Thai asthmatic patients.