Original Article – Page 11 – Asian Pacific Journal of Allergy and Immunology

July 26, 2021

Validity and reliability of the Indonesian version of the Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL)

Assessment of quality of life is needed to assess therapeutic response. There is currently no instrument available for assessing the quality of life of chronic urticaria patients in Indonesia. CU-Q2oL is a specific questionnaire for chronic urticaria that was first developed in Italian. Validity and reliability tests are important to ensure that the language or term used are appropriate to the local culture and there is no change in the validity and reliability of the questionnaire.

Chronic Urticaria, CU-Q2oL, Quality of life, Reliability, Validation

July 26, 2021

Comparison of perennial and preseasonal allergoid immunotherapy in grass pollen allergic patients

The clinical and immunological efficacy of preseasonal allergoid immunotherapy has been previously investigated, however, studies comparing the effectiveness of the two protocols are limited in the literature.

IgE, IgG4, IL-10, Perennial, preseasonal, RQLQ, SCIT, symptom scores

July 26, 2021

Manila grass (Zoysia matrella) Zoy m 1 allergen may contribute to allergic sensitization in tropical/subtropical regions due to extensive cross-reactivity with other group-1 grass pollen allergens

Pollen of grasses in Chloridoideae and Panicoideae subfamilies is a major source of grass group-1 allergens in tropical/subtropical areas. Previously, most studies of subtropical grass pollen allergens have focused on Cynodon dactylon (Bermuda grass-Chloridoideae) and Sorghum halepense (Johnson grass-Panicoideae). However, little information is available about allergenicity of pollen from Zoysia matrella (Manila grass or Zoysia grass-Chloridoideae), which is among the most popular turfgrasses in tropical/subtropical areas.

Allergic rhinitis, Chloridoideae, cross-reactivity, subtropical grass, Zoy m 1, Zoysia grass

July 26, 2021

Prevalence and diagnostic values of laboratory animal allergy among research personnel

Laboratory animal allergy (LAA) has not been sufficiently investigated, although LAA is a relatively common work-related condition and important occupational hazard.

Allergy, Laboratory animal, prevalence, Serum specific IgE, Skin prick test

July 26, 2021

Thymocytes induce renal tubular epithelial cells to undergo the epithelial-to-mesenchymal transition

Renal tubulointerstitial fibrosis is known to occur as a result of epithelial cell transformation into myofibroblasts via the epithelial-to-mesenchymal transition (EMT) process. It has been reported that macrophages, regulatory T (Treg) cells, and gamma delta T (γδ T) cells can promote fibrosis via EMT in vivo.

CD8+ T cells, Epithelial-to-mesenchymal transition (EMT), NRK-52E cells, Renal fibrosis, Thymocytes

July 26, 2021

Efficacy and safety of rupatadine fumarate in the treatment of perennial allergic rhinitis: A multicenter, double-blinded, randomized, placebo-controlled, bridging study in Koreans

The efficacy of rupatadine for the treatment of AR has been confirmed in numerous clinical studies, however there are very few studies on asian patients.

Clinical trial, Histamine antagonists, Perennial Allergic rhinitis, Platelet-activating factor, Randomized controlled trial, TNSS

July 26, 2021

Clinical characteristics and treatment outcomes of severe asthma patients with a history of multiple biologic drugs use

Asthma control has been shown to improve after clinical use of molecular-targeted biologic drugs. Although most patients have shown favorable responses to biologic drugs, some individuals need to switch to another biologic drug. To date, limited data are available regarding patients who received multiple biologic drugs.

allergic comorbidity, Allergic rhinitis, biologic drug, chronic rhinosinusitis with nasal polyps, Severe asthma

July 26, 2021

Evaluation of the clinical performance of four fungus-specific immunoglobulin E detection systems in patients with Aspergillus allergy

Allergic bronchopulmonary aspergillosis (ABPA) is an airway disease caused by Aspergillus (mainly Aspergillus fumigatus).

ABPA, Aspergillus fumigatus, fluorescence immunoassay, IgE, methodology

July 26, 2021

Prick and intradermal skin tests in patients with severe hymenoptera sting allergy using commercial versus in-house allergen extracts

Fire ant, honey bee, and wasp allergen extracts are useful in the diagnosis and treatment of severe Hymenoptera allergic patients.

Allergen extracts, Anaphylaxis, Component-resolved diagnosis, Insect allergy, Specific IgE to venom

July 26, 2021

The relationship between the rs4986791 variant of the TLR4 gene and the severity of bronchial asthma in children

Toll-like receptor 4 (TLR4) is an important receptor for lipopolysaccharide and lipid A, components of gram-negative bacteria. At present, a variant in TLR4 has been shown to be associated with asthma, but it has not been reported whether variants in TLR4 are associated with bronchial asthma in children.

bronchial asthma, Children, TLR4, variant