Asian Pacific Journal of Allergy and Immunology

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January 14, 2024

A new pepper allergen Zan b 1.01 of 2S albumins:Identification, cloning, characterization, and cross-reactivity

Zanthoxylum bungeanum (Sichuan pepper; 花椒 in Chinese) is used as a spice worldwide and is a potentially life-threatening allergenic food source, as first reported by our team in 2005. However, its allergen components are unknown.
read more
2S albumin, cashew seed, citrus allergy, pepper allergy, Zan b 1.01, Zanthoxylum bungeanum Maxim, α-amylase inhibitor
January 14, 2024

Production of anti-human cannabinoid receptor 2 (CB2) monoclonal antibody using non-viral vectorinduced human CB2 expressing myeloma as an immunogen

Cannabinoid receptor 2 (CB2) of the cannabinoid system is predominantly expressed on immune cells and involved in a diverse range of immune functions. However, the role of CB2 in immunoregulation is still controversial. One of the challenges in the detailed characterization and functional study of CB2 is the lack of CB2-specific monoclonal antibodies (mAbs).
read more
Anti-cannabinoid receptor 2 antibody, Cannabinoid receptor, Cannabinoid system, Monoclonal antibody production, Non-viral vector expression system
January 14, 2024

Anaphylaxis in children: Effect of age and atopic status

Anaphylaxis is a life-threatening allergic reaction with rising incidence worldwide. Young children’s limited ability to express symptoms adds unique diagnostic challenges.
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adrenaline, Anaphylaxis, atopy, Children, young
January 14, 2024

Differences in asthma-related outcomesby anti-IL-5 biologics, omalizumab, and dupilumabbased on blood eosinophil counts

Selecting optimal biologics based on type 2 biomarkers has been of interest in severe asthma treatment. However, few direct biomarker stratification-based comparisons have been made.
read more
asthma biologics, eosinophil, IL-5, Severe asthma
January 14, 2024

Responses of primary human nasal epithelial cellsto COVID-19 vaccine candidate

Upper respiratory tract is the primary target of SARS-CoV-2. Therefore, nasal immune responses act as the first line of defense against SARS-CoV-2 infection.
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COVID-19 vaccine, delivery systems, primary human nasal epithelial cells, RBD, SARS-CoV-2
January 14, 2024

Atmospheric environment and persistence of pediatricasthma: A population-based cohort study

Asthma is a heterogeneous disease with different outcomes. For children with asthma at the age of 7 years, 67–75% are symptom-free as adults. Data on the important link between childhood and adult asthma are sparse.
read more
air pollution, Asthma, Children, National Claims Data, Persistence
January 14, 2024

Factor associated with food allergy among preschool children with atopic dermatitis, and resolution of atopic dermatitis

Food allergy (FA) has been reported in one-third of children with moderate-to-severe atopic dermatitis (AD).
read more
atopic dermatitis, food allergy, preschool children, resolution, risk factor
January 14, 2024

Severe cutaneous adverse drug reactions: incidence, clinical characteristics, treatment, and outcomein pediatric patients

Severe cutaneous adverse drug reactions (SCARs) can cause significant morbidity and mortality. Clinical data regarding such conditions is still limited in the pediatric population.
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Acute generalized exanthematous pustulosis, Drug hypersensitivity, drug reaction with eosinophilia and systemic symptoms, pediatric drug reactions, SCARs, severe cutaneous drug reactions, Stevens-Johnson syndrome, Toxic Epidermal Necrolysis
January 14, 2024

Characterization of gut microbiome profile in childrenwith confirmed wheat allergy

Food allergies pose serious health risks, including life-threatening anaphylactic reactions, increased morbidity, and reduced quality of life. Wheat allergy is a common concern in Asia. There is growing interest in understanding the potential association between dysregulation of the gut microbiome and the development of food allergies.
read more
Anaphylaxis, Children, gut microbiome, urticaria, wheat allergy
November 12, 2023

Articular involvement in Henoch-Schönlein Purpura: A review of literature

Henoch-Schönlein purpura (HSP), the most typical kind of pediatric vasculitis, can also affect adults. Over the last 10 years, research has been increasing on improvements in HSP diagnosis, physiopathology, symptoms, and therapy. Joint involvement is highly frequent in this condition; however, it typically undergoes spontaneous resolution and does not lead to long-term complications.
read more
arthralgia, arthritis, Henoch - Schoenlein purpura, IgA vasculitis, physiopathology, treatment

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Key words

allergen Allergic rhinitis Allergy Anaphylaxis Asthma atopic dermatitis child Children chronic rhinosinusitis chronic spontaneous urticaria Chronic Urticaria COVID-19 COVID-19 vaccine cytokine depression diagnosis drug allergy Drug hypersensitivity efficacy Epidemiology food allergy Food hypersensitivity house dust mite IgE Immunotherapy obstructive sleep apnea Omalizumab prevalence primary immunodeficiency Quality of life Questionnaire Reliability risk factor risk factors safety SARS-CoV-2 Sensitization Severe asthma Skin prick test Specific IgE Thai treatment urticaria vaccine Vitamin D
Asian Pacific Journal of Allergy and Immunology

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