nattiyap@gmail.com – Page 3 – Asian Pacific Journal of Allergy and Immunology

October 15, 2024

Mpox global health emergency: Insights into the virus,immune responses, and advancements in vaccines (PART II)

Mpox is currently a global health emergency. This review (Part II) aims to provide insights into Mpox vaccines and their advancements, offering easily digestible information for healthcare workers and researchers. Current Mpox vaccines are all live-attenuated, previously approved for smallpox, and are classified into non-replicating (Modified Vaccinia Ankara-Bavarian Nordic or MVA-BN) and replicating vaccines (Lister clone16m8 KM Biologic or LC16m8KMB and Acambis2000 or ACAM2000).

Monkeypox virus, Mpox, MPXV, Novel Platform, PEP (Post-Exposure Prophylaxis), vaccine

October 15, 2024

Mpox global health emergency: Insights into the virus, immune responses, and advancements in vaccines (PART I)

Mpox, the zoonotic disease caused by Monkeypox virus (MPXV), is currently a global health emergency. This review (Part I) aims to provide insights into the virus life cycle, epidemiology, host immune responses, and immune evasion mechanisms.

Epidemiology, Immune response, Monkeypox virus, Mpox, MPXV, Viral Life Cycle

July 3, 2024

Association and correlation of patient symptom perception and asthma control – a rapid literature review

Several studies suggest that patients often under-estimate their asthma symptoms and over-estimate their level of asthma control, potentially putting them at risk of undertreatment with inhaled corticosteroids.

Association, asthma control, correlation, symptom perception, symptom-based treatment

May 20, 2024

Unraveling the immunogenetics of STAT proteins: Clinical perspectives on gain-of-function and loss-of-function variants

Signal Transducer and Activator of Transcription (STAT) proteins play pivotal roles in immune regulation. The dysregulation of these proteins, attributed to both gain-of-function (GOF) and loss-of-function (LOF) variants, has emerged as a substantial and intricate area of research.

gain-of-function variants, immune dysregulation, loss-of-function variants, primary immunodeficiency, STAT Proteins

May 20, 2024

Host factors influencing variable symptoms of COVID-19

Similar to many other viruses, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) causes various symptoms in individuals who have been exposed to the virus. Individuals exposed to the virus can be asymptomatic, mild, severe, and critical for mortality.

cellular variants, emergent viruses, MHC polymorphism, SARS-CoV-2, uncertain symptoms, viral immunology, viral receptor

April 8, 2024

Incidence, predictors, and treatment outcomes of biphasicanaphylaxis in the emergency department of a tertiary hospital: A 5-year retrospective study

Biphasic anaphylaxis despite successful treatment has an incidence of 4-5% based on NIAID/FAAN criteria. Our study aimed to investigate the frequency and predictive factors associated with biphasic reactions within the emergency department (ED) at Siriraj Hospital.

Anaphylaxis, Asia-Pacific, Biphasic anaphylaxis, drug allergy, Emergency department, food allergy, prevalence, risk factors

April 8, 2024

Lupus exacerbation in ovalbumin-induced asthmain Fc gamma receptor IIb deficient mice,partly due to hyperfunction of dendritic cells

Although allergy might be another factor that exacerbates lupus as demonstrated by several epidemiologic studies, the direct correlation between lupus activities and allergy is still in question.

Asthma, Dendritic cells, FcgRIIb, lupus, Ovalbumin, T cells

April 8, 2024

PCR combined with lateral flow dipstick assay (PCR-LFD) for a rapid diagnosis of melioidosis

Melioidosis is an infectious disease caused by Burkholderia pseudomallei. Septicemic melioidosis patients have a high mortality rate within 48 hours.

Burkholderia pseudomallei, lateral flow dipstick assay, Melioidosis, polymerase chain reaction

April 8, 2024

Short-term impact of exposure to ambient air volatile organic compounds on daily clinic visits for urticariain Kaohsiung, Taiwan

Air volatile organic compounds (VOCs) cause allergic reaction mainly via the respiratory tract or skin.

ambient air volatile organic compounds, case-crossover study, Kaohsiung, short-term impact, Taiwan, urticaria

April 8, 2024

Pulmonary function characteristics in childrenwith suspected asthma: implications for asthma diagnosis

In children suspected of asthma, diagnosis is confirmed via variable expiratory airflow limitation. However, there is no single gold standard test for diagnosing asthma.

Asthma, Children, diagnosis, paediatric, spirometry