nattiyap@gmail.com – Page 2 – Asian Pacific Journal of Allergy and Immunology

January 6, 2025

Chronic cough management: Practical guidelines and PICO-based evidence for treatment

This part reviews the management of chronic cough and proposes a management algorithm. Despite proven improvements in quality of life following chronic cough treatment, a clear understanding of the disease and the evidence for the efficacy of some treatments remain vague.

Chronic Cough, cough, evidence-based, guideline, PICO, treatment

January 6, 2025

Chronic cough management: Practical guidelines and PICO-based evidence for screening and investigation

Chronic cough is a common clinical condition requiring comprehensive assessment. This review employs a symptom-focused approach, prioritizing the presenting symptom of “chronic cough” to mirror real-world clinical practice.

Chronic Cough, cough, diagnosis, evidence-based, gastroesophageal reflux, guideline, persistent cough, primary care, refractory chronic cough, respiratory, unexplained chronic cough

November 28, 2024

Chronic rhinitis and its impact on COPD: A literature review

Chronic obstructive pulmonary disease (COPD) exerts a notable impact on the quality of life of individuals, precipitating substantial economic burdens. A probable association exists between chronic obstructive pulmonary disease (COPD) and chronic rhinitis (CR).

Allergic rhinitis, chronic obstructive pulmonary disease, chronic rhinitis, literature review, non-allergic rhinitis

November 28, 2024

Chimeric peptides targeting the receptor-binding domainof SARS-CoV-2 variants inhibit ACE2 interaction

The receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) protein is pivotal in facilitating viral entry and serves as a major target for vaccine development and therapeutics. Despite undergoing mutations aimed at evading host immunity, certain regions within the RBD remain conserved.

angiotensin-converting enzyme 2 (ACE2), peptides, phage display, receptor-binding domain (RBD), respiratory disease, SARS-CoV-2

November 28, 2024

Factors associated with poor asthma control in children: A prediction model

Inhaled corticosteroids (ICS) are the first-line therapy for pediatric asthma. However, very few studies have developed simple tools for predicting treatment outcomes in pediatric asthma.

Asthma, child, Inhaled corticosteroids, prediction model, therapy

November 28, 2024

Genetic variations in Vitamin D Binding Protein (VDBP) impact vitamin D level and asthma susceptibility across the four ethnic populations

Asthma are associated with the vitamin D axis. Genetic variations of VDBP, notably rs7041 and rs4588, influence circulating vitamin D levels. However, data on their link to asthma are inconsistent, and ethnic differences remain unclear.

Asthma, cross-ethnic comparison, genetic polymorphism, Vitamin D, vitamin D binding protein

November 28, 2024

Compound D from Zingiber cassumunar Roxb. attenuatedtype 2 inflammatory cytokine-induced tight junction disruptionin airway epithelial cells

Barrier disruption in the airway mucosae has been implicated in allergic type 2 inflammatory diseases such as allergic rhinitis and asthma. Zingiber cassumunar Roxb. has long been used in traditional medicine to treat allergic diseases. The active compound, namely compound D, has proven anti-inflammatory benefits. However, the effect of compound D on allergic inflammation remains unclear.

airway epithelial cells, allergic inflammation, Asthma, tight junction, Zingiber cassumunar Roxb

November 28, 2024

Binding specificity of HuScFv to cholangiocarcinoma cells; New avenues for diagnosis and treatment

Cholangiocarcinoma (CCA) is a very aggressive cancer of the bile ducts. Recent advances in immunotherapy, particularly with human single-chain variable fragments (HuScFv), have shown promise in the treatment of solid tumors by targeting cancer cells or improving the immune response.

CCA, flow cytometry, Immunotherapy, Single-chain variable fragment, targeted cancer therapy

November 28, 2024

A 10-year comparative study of factors for allergic asthma and/or rhinitis in two cross-sectional surveys

The allergenic relevance of the living environment changes over the last decades is largely unknown.

allergic sensitization, Asthma, rhinitis, risk factor, secondhand smoke, serum IgE

November 28, 2024

Medication adherence, sensory attributes, and adverse effects of intranasal corticosteroids in allergic rhinitis patients: A systematic review and meta-analysis

Intranasal corticosteroid (INCS) remains the primary treatment for allergic rhinitis (AR). Understanding adherence, safety concerns and sensory preferences is crucial for optimal care.

adverse effects, Allergic rhinitis, intranasal corticosteroids, medication adherence, patient preference