Anti-atopic dermatitis effect of Scutellaria barbata D. Don via regulation of MAPK signaling pathways
Atopic dermatitis (AD) is a chronic disease that causes skin itching.
Biological properties of reverse ankyrin engineered for dimer construction to enhance HIV-1 capsid interaction
Assembly and budding in the late-stage of human immunodeficiency virus type 1 (HIV-1) production rely on Gag protein polymerization at the inner leaflet of the plasma membrane. We previously generated a monomeric ankyrin repeat protein (Ank1D4) that specifically interacts with capsid protein (CAp24) of HIV-1, however this protein had modest binding affinity.
The implementation of pediatric asthma guidelines including self-assessment of the level of confidence and accessibility of medical supplies necessary for asthma management from the perspectives of multidisciplinary care teams
Asthma control in Thai children is not yet satisfactory. Direct observation of the clinical practice for health care professionals (HCPs) in asthma clinic is essential.
Skin necrosis following local anesthetic: Same presentation for two different diagnoses
Local anesthetics (LA) are widely used in medicine and are generally well tolerated. Although most adverse reactions are nonallergic, LA are a frequent reason for allergy consultation.
Asia-Pacific survey of physicians’ perceptions and managements of chronic rhinosinusitis
The diagnosis and management of patients with chronic rhinosinusitis (CRS) may vary between otolaryngologists and allergists. Moreover, the adherence of different practitioners to European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS)2020 guideline recommendations has not been previously ascertained in Asia-Pacific regions.
Call for review and meta-analysis papers
To be published Asian Pacific Journal of Allergy and Immunology (APJAI) in June, September and December 2022
Adverse drug reactions of montelukast and pranlukast: Analysis of the Korea database
Leukotriene receptor antagonists are recommended to treat asthma and allergic rhinitis. Although they had been used for a long time, recent studies have reported neuropsychiatric adverse drug reactions are associated with montelukast.
Maintained disease control and steroid-sparing effect of subcutaneous immunotherapy in allergic rhinitis and asthma
Allergen immunotherapy is the only currently available treatment strategy that modifies the immune response to the causative allergen and induces clinical improvement and a steroid-sparing effect.
As-needed versus regular intranasal corticosteroid for allergic rhinitis: A systematic review and meta-analysis
Daily intranasal corticosteroid (INCS) is recommended for treating allergic rhinitis (AR). Nevertheless, patients are generally not adherent and use it on-demand. The data on the efficacy of as-needed INCS was insufficient.
N-acetylcysteine potentiates the tumor cytotoxicity of cytokine-induced killer cells
Cytokine-induced killer (CIK) cells are an ex vivo expanded heterogeneous population of natural killer (NK)-like T cells that can exert potent MHC-unrestricted antitumor activity. A number of pre-clinical and clinical studies have demonstrated that CIK cells can serve as a safe and potent immunotherapy of malignant tumors. N-acetylcysteine (NAC) has been demonstrated to enhance the T-cell functions by increasing their proliferation and cytokine production.