Denatonium benzoate promotes IgE-mediated mast celldegranulation and ovalbumin-induced allergic diarrheain BALB/c mice
Denatonium benzoate (DB), one of the most bitter compounds known to man, is used for alcohol denaturation. Some reports have demonstrated that asthmatic symptoms are associated with DB exposure, but the possible links between DB and immunoglobulin E (IgE)-mediated allergy susceptibility have not yet been examined.