Drug hypersensitivity – Asian Pacific Journal of Allergy and Immunology

January 14, 2024

Severe cutaneous adverse drug reactions: incidence, clinical characteristics, treatment, and outcomein pediatric patients

Severe cutaneous adverse drug reactions (SCARs) can cause significant morbidity and mortality. Clinical data regarding such conditions is still limited in the pediatric population.

Acute generalized exanthematous pustulosis, Drug hypersensitivity, drug reaction with eosinophilia and systemic symptoms, pediatric drug reactions, SCARs, severe cutaneous drug reactions, Stevens-Johnson syndrome, Toxic Epidermal Necrolysis

May 30, 2022

Skin necrosis following local anesthetic: Same presentation for two different diagnoses

Local anesthetics (LA) are widely used in medicine and are generally well tolerated. Although most adverse reactions are nonallergic, LA are a frequent reason for allergy consultation.

drug allergy evaluation, Drug hypersensitivity, local anesthetic hypersensitivity, local anesthetics, skin necrosis

January 4, 2022

Concomitant chronic spontaneous urticaria treatment might hinder the diagnosis of occupational latex-induced anaphylaxis: A case report

Cutaneous manifestations of chronic spontaneous urticaria (CSU) are identical to type 1 hypersensitivity reactions. The daily occurrence of rash from occupational allergy could be misinterpreted as CSU exacerbation.

Anaphylaxis, Drug hypersensitivity, hypersensitivity, latex hypersensitivity, natural rubber latex, nursing, skin tests, urticaria

January 30, 2021

Successful treatment of neurocysticercosis with albendazole desensitization

Neurocysticercosis is a growing public health problem in the United States. Albendazole is a mainstay of medical therapy for neurocysticercosis, and here we present a case of hypersensitivity to albendazole leading to life-threatening disease progression.

Adverse drug reaction, Albendazole, Anti-parasite, Desensitization, Drug hypersensitivity, Neurocysticercosis, Orally

December 20, 2020

Immediate allergic reaction to thiocolchicoside confirmed by skin testing and basophil activation test: A case report and literature review

Thiocolchicoside is a muscle relaxant, anti-inflammatory, and analgesic. Administered orally, intramuscularly, or topically, this drug is used in the symptomatic treatment of muscular spasms and rheumatologic disorders. Despite its extensive use, thiocolchicoside is a very rare sensitizer.

basophil activation test, CD63+ basophils, central muscle relaxant, Drug hypersensitivity, immediate allergic reaction, Thiocolchicoside

October 31, 2020

Iodinated contrast media allergy is rare in patients undergoing sialography

Iodinated contrast media allergy is considered as a strong contra-indication for performing sialography. There is little evidence to support this approach.

Drug hypersensitivity, iodinated contrast media, iodine allergy, salivary glands, sialography

May 25, 2020

Epoetin-alfa induced pruritic maculopapular eruption: Case report and literature review

Erythropoiesis-stimulating agents (ESA) are commonly used in clinical practice to improve anaemia. Despite a number of patients successfully treated without adverse events, the complications have been previously reported.

Anaphylaxis, Drug eruptions, Drug hypersensitivity, Epoetin hypersensitivity, Erythropoietin