Unveiling the role of neutrophilsin chronic spontaneous urticaria: Beyond mast cells
Mast cells and eosinophils are considered pivotal contributors to the pathogenesis of chronic spontaneous urticaria (CSU).
Efficacy of drug therapies in antihistamine refractory chronic spontaneous urticaria: Real life data
Omalizumab is a safe and effective treatment for antihistamine-refractory chronic spontaneous urticaria (CSU) but is insufficient in one-third of patients. For serious cases in which omalizumab is ineffective, cyclosporine or methotrexate may be preferred. Most drug trials in CSU have focused on omalizumab or cyclosporine monotherapy.
Clinical characteristics and treatment response of chronic spontaneous urticaria according to age: A single-center Korean study
Little information exists regarding the incidence of chronic spontaneous urticaria (CSU) or differences in its characteristics according to age.
Risk factors of uncontrolled symptoms using the standard dose of second-generation H1 -antihistamines in chronic spontaneous urticaria children
A standard dose of second-generation H1 -antihistamines is recommended as the first-line treatment of chronic spontaneous urticaria (CSU), previous studies have found that approximately 20-50% of CSU children fail to control their symptoms and required step-up treatments.