Risk factors for poor adherence to inhaled corticosteroid therapy in patients with moderate to severe asthma
Poor adherence to inhaled corticosteroid (ICS) therapy is a common reason for worsened asthma control.
Distinct effects of different adjuvants in the mouse model of allergic airway inflammation
Allergic asthma was typically considered as an inflammatory disease mediated by type 2 immunity. However, recent studies revealed that asthma is a complex disease displaying a variety of phenotypes and endotypes.
Effect of inhaled corticosteroids on bone mineral density in patients with asthma
Inhaled corticosteroids (ICS) are a safe treatment for asthma. However, at higher doses, ICS use has been reported to inhibit adrenocortical function.
Prevalence of rat and mouse sensitization in Asian patients with respiratory allergy
Skin prick test (SPT) is useful in identifying rat and mouse sensitization.
Efficacy and safety of omalizumab in patients with moderate-to-severe asthma: An analytic comparison of data from randomized controlled trials between Chinese and Caucasians
Omalizumab has > 15 years of real-world evidence of effectiveness in Caucasian patients. In August 2017, it was approved as an add-on therapy for the management of moderate-to-severe asthma in China.
Clinical characteristics and aspirin desensitization in Thai patients with a suggestive history of NSAID-exacerbated respiratory disease
Non-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (NERD) is characterized by the triad of chronic rhinosinusitis with nasal polyp, asthma, and aspirin (ASA) or NSAID hypersensitivity. Previous
study of NERD has rarely been reported in Asian population.
Effect of gene polymorphisms in ADAM33, TGFβ1, VEGFA, and PLAUR on asthma in Thai population
Most of the asthma susceptibility genes have demonstrated moderate effect. Gene-gene interaction may play a role in asthma.
Comparison efficacy of randomized nebulized magnesium sulfate and ipratropium bromide/fenoterol in children with moderate to severe asthma exacerbation
In Thailand, nebulized ipratropium bromide/fenoterol, is commonly used in addition to salbutamol for severe asthma exacerbation. Recently, nebulized MgSO4 is indicated in GINA 2015 as an additive treatment for severe
cases. However, there is limited data showed the efficacy of both drugs in childhood severe asthma. The purpose of this study to compare efficacy and safety of nebulized MgSO4 and ipratropium bromide/fenoterol in moderate to severe asthma attacks.
Prevalence of small airways dysfunction in asthma with- and without-fixed airflow obstruction and chronic obstructive pulmonary disease
Small airways dysfunction (SAD) is not uncommon in asthma without fixed airflow obstruction (FAO).
Real-world observational study of the evaluation of inhaler techniques in asthma patients
Inhaler devices are a keystone in the management of asthma during the maintenance phase of treatment.