Asthma – Page 3 – Asian Pacific Journal of Allergy and Immunology

March 16, 2020

Efficacy and safety of omalizumab in patients with moderate-to-severe asthma: An analytic comparison of data from randomized controlled trials between Chinese and Caucasians

Omalizumab has > 15 years of real-world evidence of effectiveness in Caucasian patients. In August 2017, it was approved as an add-on therapy for the management of moderate-to-severe asthma in China.

Asthma, Caucasian, Chinese, comparative analysis, Omalizumab

October 29, 2019

Clinical characteristics and aspirin desensitization in Thai patients with a suggestive history of NSAID-exacerbated respiratory disease

Non-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (NERD) is characterized by the triad of chronic rhinosinusitis with nasal polyp, asthma, and aspirin (ASA) or NSAID hypersensitivity. Previous study of NERD has rarely been reported in Asian population.

aspirin desensitization, Asthma, drug allergy, nasal polyp, NSAID-exacerbated respiratory disease, rhinosinusitis, sinus surgery

September 10, 2019

Effect of gene polymorphisms in ADAM33, TGFβ1, VEGFA, and PLAUR on asthma in Thai population

Most of the asthma susceptibility genes have demonstrated moderate effect. Gene-gene interaction may play a role in asthma.

ADAM33, Asthma, gene interactions, Gene polymorphisms, PLAUR, TGFβ1, Thai population, VEGFA

July 31, 2019

Comparison efficacy of randomized nebulized magnesium sulfate and ipratropium bromide/fenoterol in children with moderate to severe asthma exacerbation

In Thailand, nebulized ipratropium bromide/fenoterol, is commonly used in addition to salbutamol for severe asthma exacerbation. Recently, nebulized MgSO4 is indicated in GINA 2015 as an additive treatment for severe cases. However, there is limited data showed the efficacy of both drugs in childhood severe asthma. The purpose of this study to compare efficacy and safety of nebulized MgSO4 and ipratropium bromide/fenoterol in moderate to severe asthma attacks.

acute asthmatic attack, Asthma, isotonic magnesium sulfate, nebulized ipratropium bromide/fenoterol, nebulized magnesium sulfate, severe acute asthma

May 22, 2019

Prevalence of small airways dysfunction in asthma with- and without-fixed airflow obstruction and chronic obstructive pulmonary disease

Small airways dysfunction (SAD) is not uncommon in asthma without fixed airflow obstruction (FAO).

air trapping, Asthma, COPD, fixed airflow obstruction, impulse oscillometry, small airways

February 4, 2019

Real-world observational study of the evaluation of inhaler techniques in asthma patients

Inhaler devices are a keystone in the management of asthma during the maintenance phase of treatment.

Asthma, device, inhalation, medication, technique