Asthma – Asian Pacific Journal of Allergy and Immunology

February 12, 2025

Risk of allergic diseases in age-related macular degeneration: A nationwide cohort study in South Korea

Premorbid allergic diseases are linked with the development of age-related macular degeneration (AMD), however, the risk of allergic diseases among patients with AMD is largely unknown. Objective: To evaluate the association between AMD with or without visual disability (VD) and the risk of allergic diseases.

November 28, 2024

Factors associated with poor asthma control in children: A prediction model

Inhaled corticosteroids (ICS) are the first-line therapy for pediatric asthma. However, very few studies have developed simple tools for predicting treatment outcomes in pediatric asthma.

Asthma, child, Inhaled corticosteroids, prediction model, therapy

November 28, 2024

Genetic variations in Vitamin D Binding Protein (VDBP) impact vitamin D level and asthma susceptibility across the four ethnic populations

Asthma are associated with the vitamin D axis. Genetic variations of VDBP, notably rs7041 and rs4588, influence circulating vitamin D levels. However, data on their link to asthma are inconsistent, and ethnic differences remain unclear.

Asthma, cross-ethnic comparison, genetic polymorphism, Vitamin D, vitamin D binding protein

November 28, 2024

Compound D from Zingiber cassumunar Roxb. attenuatedtype 2 inflammatory cytokine-induced tight junction disruptionin airway epithelial cells

Barrier disruption in the airway mucosae has been implicated in allergic type 2 inflammatory diseases such as allergic rhinitis and asthma. Zingiber cassumunar Roxb. has long been used in traditional medicine to treat allergic diseases. The active compound, namely compound D, has proven anti-inflammatory benefits. However, the effect of compound D on allergic inflammation remains unclear.

airway epithelial cells, allergic inflammation, Asthma, tight junction, Zingiber cassumunar Roxb

November 28, 2024

A 10-year comparative study of factors for allergic asthma and/or rhinitis in two cross-sectional surveys

The allergenic relevance of the living environment changes over the last decades is largely unknown.

allergic sensitization, Asthma, rhinitis, risk factor, secondhand smoke, serum IgE

April 8, 2024

Lupus exacerbation in ovalbumin-induced asthmain Fc gamma receptor IIb deficient mice,partly due to hyperfunction of dendritic cells

Although allergy might be another factor that exacerbates lupus as demonstrated by several epidemiologic studies, the direct correlation between lupus activities and allergy is still in question.

Asthma, Dendritic cells, FcgRIIb, lupus, Ovalbumin, T cells

April 8, 2024

Pulmonary function characteristics in childrenwith suspected asthma: implications for asthma diagnosis

In children suspected of asthma, diagnosis is confirmed via variable expiratory airflow limitation. However, there is no single gold standard test for diagnosing asthma.

Asthma, Children, diagnosis, paediatric, spirometry

January 14, 2024

Atmospheric environment and persistence of pediatricasthma: A population-based cohort study

Asthma is a heterogeneous disease with different outcomes. For children with asthma at the age of 7 years, 67–75% are symptom-free as adults. Data on the important link between childhood and adult asthma are sparse.

air pollution, Asthma, Children, National Claims Data, Persistence

April 17, 2023

Comorbidities & burden of disease in atopic dermatitis

Atopic dermatitis is associated with an increased frequency of other atopic & allergic manifestations, including asthma in 10% to 30% of cases depending on age, allergic rhinitis, food allergies, eosinophilic diseases, and allergic conjunctivitis. The comorbidities outside the atopic march are overall less frequent than in psoriasis.

Allergic rhinitis, Asthma, atopic dermatitis, Comorbidity, Mental Health, Vitiligo

January 23, 2023

Allergen immunotherapy for respiratory allergies in clinical practice: A comprehensive review

Allergen-specific immunotherapy (AIT) is the only treatment that modifies the underlying pathophysiology of IgE-mediated allergic diseases.

allergen, Allergic rhinitis, Allergy, Asthma, Immunotherapy