Asthma – Asian Pacific Journal of Allergy and Immunology

April 8, 2024

Lupus exacerbation in ovalbumin-induced asthmain Fc gamma receptor IIb deficient mice,partly due to hyperfunction of dendritic cells

Although allergy might be another factor that exacerbates lupus as demonstrated by several epidemiologic studies, the direct correlation between lupus activities and allergy is still in question.

Asthma, Dendritic cells, FcgRIIb, lupus, Ovalbumin, T cells

April 8, 2024

Pulmonary function characteristics in childrenwith suspected asthma: implications for asthma diagnosis

In children suspected of asthma, diagnosis is confirmed via variable expiratory airflow limitation. However, there is no single gold standard test for diagnosing asthma.

Asthma, Children, diagnosis, paediatric, spirometry

January 14, 2024

Atmospheric environment and persistence of pediatricasthma: A population-based cohort study

Asthma is a heterogeneous disease with different outcomes. For children with asthma at the age of 7 years, 67–75% are symptom-free as adults. Data on the important link between childhood and adult asthma are sparse.

air pollution, Asthma, Children, National Claims Data, Persistence

April 17, 2023

Comorbidities & burden of disease in atopic dermatitis

Atopic dermatitis is associated with an increased frequency of other atopic & allergic manifestations, including asthma in 10% to 30% of cases depending on age, allergic rhinitis, food allergies, eosinophilic diseases, and allergic conjunctivitis. The comorbidities outside the atopic march are overall less frequent than in psoriasis.

Allergic rhinitis, Asthma, atopic dermatitis, Comorbidity, Mental Health, Vitiligo

January 23, 2023

Allergen immunotherapy for respiratory allergies in clinical practice: A comprehensive review

Allergen-specific immunotherapy (AIT) is the only treatment that modifies the underlying pathophysiology of IgE-mediated allergic diseases.

allergen, Allergic rhinitis, Allergy, Asthma, Immunotherapy

January 2, 2023

The association between MTHFR polymorphism, dietary methyl donors, and childhood asthma and atopy

Studies investigating the genetic association of the C677T methylenetetrahydrofolate reductase (MTHFR) genotype and dietary methyl donors with asthma and atopy are limited, and have variable results.

Asthma, atopy, Folate, Methyl donors, MTHFR, polymorphism

March 14, 2022

Maintained disease control and steroid-sparing effect of subcutaneous immunotherapy in allergic rhinitis and asthma

Allergen immunotherapy is the only currently available treatment strategy that modifies the immune response to the causative allergen and induces clinical improvement and a steroid-sparing effect.

Allergen immunotherapy, Allergic rhinitis, Asthma, efficacy, inhaled steroid, intranasal steroid, steroid sparing

March 14, 2022

Particulate matter exposure during pregnancy increases risk of childhood asthma: modified by gender and NRF2 genotype

Exposure to particulate matter (PM) has been known to develop asthma in children and the oxidative stress-related mechanisms are suggested. For the development of asthma, not only the exposure dose but also the critical window and the risk modifying factors should be evaluated.

Asthma, gender, gene, NRF2, particulate matter, pregnancy

November 2, 2021

Severe allergic asthma: Does alexithymia interfere with omalizumab treatment outcome?

Alexithymia is among psychological factors reported to interfere with asthma management. Severe allergic asthma (SAA) is characterized by uncontrolled asthma despite maximal standard pharmacological treatment which can benefit from an add-on treatment with Omalizumab, an anti-IgE monoclonal antibody.

alexithymia, Allergy, Asthma, Omalizumab, Quality of life

September 20, 2021

Eosinophilia, asthma, NERD and the use of oral corticosteroids predict uncontrolled chronic rhinosinusitis with nasal polyps after surgery

Severe uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP) is a challenging condition to treat. The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 (EPOS2020) has the following criteria when considering biological therapy for severe uncontrolled CRSwNP: eosinophilia, need for oral corticosteroids (OCS), symptom score, loss of sense of smell and co-morbid asthma.

Asthma, chronic rhinosinusitis, computed tomography, Eosinophilia, nasal polyp, sinusitis