Review Article – Asian Pacific Journal of Allergy and Immunology

January 6, 2025

Chronic cough management: Practical guidelines and PICO-based evidence for treatment

This part reviews the management of chronic cough and proposes a management algorithm. Despite proven improvements in quality of life following chronic cough treatment, a clear understanding of the disease and the evidence for the efficacy of some treatments remain vague.

Chronic Cough, cough, evidence-based, guideline, PICO, treatment

January 6, 2025

Chronic cough management: Practical guidelines and PICO-based evidence for screening and investigation

Chronic cough is a common clinical condition requiring comprehensive assessment. This review employs a symptom-focused approach, prioritizing the presenting symptom of “chronic cough” to mirror real-world clinical practice.

Chronic Cough, cough, diagnosis, evidence-based, gastroesophageal reflux, guideline, persistent cough, primary care, refractory chronic cough, respiratory, unexplained chronic cough

November 28, 2024

Chronic rhinitis and its impact on COPD: A literature review

Chronic obstructive pulmonary disease (COPD) exerts a notable impact on the quality of life of individuals, precipitating substantial economic burdens. A probable association exists between chronic obstructive pulmonary disease (COPD) and chronic rhinitis (CR).

Allergic rhinitis, chronic obstructive pulmonary disease, chronic rhinitis, literature review, non-allergic rhinitis

November 28, 2024

Medication adherence, sensory attributes, and adverse effects of intranasal corticosteroids in allergic rhinitis patients: A systematic review and meta-analysis

Intranasal corticosteroid (INCS) remains the primary treatment for allergic rhinitis (AR). Understanding adherence, safety concerns and sensory preferences is crucial for optimal care.

adverse effects, Allergic rhinitis, intranasal corticosteroids, medication adherence, patient preference

October 15, 2024

Mpox global health emergency: Insights into the virus,immune responses, and advancements in vaccines (PART II)

Mpox is currently a global health emergency. This review (Part II) aims to provide insights into Mpox vaccines and their advancements, offering easily digestible information for healthcare workers and researchers. Current Mpox vaccines are all live-attenuated, previously approved for smallpox, and are classified into non-replicating (Modified Vaccinia Ankara-Bavarian Nordic or MVA-BN) and replicating vaccines (Lister clone16m8 KM Biologic or LC16m8KMB and Acambis2000 or ACAM2000).

Monkeypox virus, Mpox, MPXV, Novel Platform, PEP (Post-Exposure Prophylaxis), vaccine

October 15, 2024

Mpox global health emergency: Insights into the virus, immune responses, and advancements in vaccines (PART I)

Mpox, the zoonotic disease caused by Monkeypox virus (MPXV), is currently a global health emergency. This review (Part I) aims to provide insights into the virus life cycle, epidemiology, host immune responses, and immune evasion mechanisms.

Epidemiology, Immune response, Monkeypox virus, Mpox, MPXV, Viral Life Cycle

July 3, 2024

Association and correlation of patient symptom perception and asthma control – a rapid literature review

Several studies suggest that patients often under-estimate their asthma symptoms and over-estimate their level of asthma control, potentially putting them at risk of undertreatment with inhaled corticosteroids.

Association, asthma control, correlation, symptom perception, symptom-based treatment

May 20, 2024

Unraveling the immunogenetics of STAT proteins: Clinical perspectives on gain-of-function and loss-of-function variants

Signal Transducer and Activator of Transcription (STAT) proteins play pivotal roles in immune regulation. The dysregulation of these proteins, attributed to both gain-of-function (GOF) and loss-of-function (LOF) variants, has emerged as a substantial and intricate area of research.

gain-of-function variants, immune dysregulation, loss-of-function variants, primary immunodeficiency, STAT Proteins

May 20, 2024

Host factors influencing variable symptoms of COVID-19

Similar to many other viruses, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) causes various symptoms in individuals who have been exposed to the virus. Individuals exposed to the virus can be asymptomatic, mild, severe, and critical for mortality.

cellular variants, emergent viruses, MHC polymorphism, SARS-CoV-2, uncertain symptoms, viral immunology, viral receptor

January 14, 2024

Diving deep into fish allergen immunotherapy: Current knowledge and future directions

Fish allergy is one of the “big nine” categories of food allergens worldwide, and its prevalence is increasing with the higher demand for this nutritious food source.

allergen, Anaphylaxis, Component Resolved Diagnostics, fish allergy, Immunotherapy, vaccine