Asian Pacific Journal of Allergy and Immunology

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Page 8
March 14, 2022

Thrombosis with thrombocytopenia after the second ChAdOx1 nCoV-19 vaccination: A possible immunological mechanism independent of anti-platelet factor 4 antibody

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a distinctive syndrome characterized by unusual site thrombosis accompanied by thrombocytopenia following adenoviral vector vaccines against severe acute respiratory syndrome coronavirus 2. Platelet-activating anti-platelet factor 4-dependent antibodies (anti-PF4 Abs) have been identified as pathogenic antibodies in almost all patients.
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adenoviral vector, antibody, platelet factor 4, thromboembolism, vaccine
January 4, 2022

Invariant Natural Killer T (iNKT) cells response in human melioidosis

Melioidosis is an infectious disease caused by Burkholderia pseudomallei. In infected mice, IFN-γ can provide protection against B. pseudomallei infection. Invariant Natural Killer T (iNKT) cells are a subpopulation of T lymphocytes, activated by recognition of glycolipid ligands such as α-Galactosylceramide presented by CD1d, produce and secrete several cytokines, including IFN-γ and IL-4. The response of iNKT cells in human melioidosis was then investigated.
read more
activation, Burkholderia pseudomallei, human infection, iNKT cells, Melioidosis
January 4, 2022

Role of interleukin 5-induced eosinophils in interleukin 33-triggered airway inflammation in mice

Interleukin (IL)-5 is essential for allergen induced eosinophilic airway inflammation, but not activation of T helper type 2 (Th2) cells in the lung. Although an excessive Th2 reaction is observed without IL-5 signaling, the mechanisms have remained unknown.
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airway inflammation, eosinophil, IL-33, IL-5Rα-/- mice, ILC2
January 4, 2022

Nivolumab-induced diffuse type 2 rhinosinusitis: A case report

Nivolumab, an immune checkpoint inhibitor is used to treat advanced metastatic malignancies. Data showed that nivolumab can cause exacerbated response of T-Helper 2 cells and lead to airway inflammation.
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chronic rhinosinusitis, Immune check point inhibitor, Immune-related adverse event, nasal polyps, Nivolumab, Programed cell death-ligand
January 4, 2022

Do aggravating rhinologic symptoms at work indicate occupational exposure? A cross-sectional outpatient clinic study

Air impurities can exacerbate or cause rhinologic diseases. However, only a few studies have assessed rhinologic patients’ symptoms at work.
read more
15D, HRQoL, Rhinology, SNOT-22, work-related
January 4, 2022

Concomitant chronic spontaneous urticaria treatment might hinder the diagnosis of occupational latex-induced anaphylaxis: A case report

Cutaneous manifestations of chronic spontaneous urticaria (CSU) are identical to type 1 hypersensitivity reactions. The daily occurrence of rash from occupational allergy could be misinterpreted as CSU exacerbation.
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Anaphylaxis, Drug hypersensitivity, hypersensitivity, latex hypersensitivity, natural rubber latex, nursing, skin tests, urticaria
November 2, 2021

Ocular manifestation and generalization after ocular onset in ocular myasthenia gravis: A 5-year analysis

Ocular Myasthenia Gravis (OMG) is an autoimmune disease which causes ptosis, diplopia, or both. There is very limited information on the presenting symptoms, treatment trends, factors influencing generalization, and treatment outcome in Thai populations.
read more
Acetylcholinesterase inhibitors, AChR antibodies, Autoantibodies/immunology, Cholinergic/immunology, Diplopia, Generalized Myasthenia Gravis, Ocular Myasthenia Gravis, Ptosis, Receptors, Treatment outcome
November 2, 2021

Prevalence of sensitization to specific allergens in allergic patients in Beijing, China: A 7-year retrospective study

Knowledge of the prevalence of common sensitizing allergens may aid in overall management of allergic disease in a specified area.
read more
Artemisia, Chinese patients, crab, dust mites, food allergens, Inhaled allergens, peanut, R package ggplot2, sensitization prevalence, Serum specific IgE
November 2, 2021

Clinical and immunological characteristics of bee venom hypersensitivity among beekeepers in Thailand

Bee venom (BV) hypersensitivity can be severe and potentially life-threatening. Beekeepers heavily exposed to bee stings and are thus at a high-risk group. The data on bee sting reactions among beekeepers in Thailand is limited.
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bee stings, bee venom, beekeepers, Thailand, venom allergy
November 2, 2021

Ability of Alere™ HIV Combo to diagnose acute HIV infection is based mainly on HIV-1 p24 antigen detection

Alere™ HIV Combo is the only rapid and sensitive point-of-care 4th generation (antigen/antibody) HIV test newly available in Thailand which is advantageous of differentiating between positivity of antigen or antibody or both, especially in acute HIV infection (AHI). AHI in this study was defined by positive machine-based 4th generation test with measurable HIV-RNA but negative 3rd generation (IgM/IgG antibody only) tests.
read more
acute HIV infection, Alere™ HIV Combo, p24 antigen, rapid 4th generation HIV test, Rapid distinguishable antigen-antibody HIV test

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Categories

  • Announcement (1)
  • Case Report (23)
  • Early Online (93)
  • Original Article (223)
  • Review Article (29)

Key words

allergen Allergic rhinitis Allergy Anaphylaxis Asthma atopic dermatitis child Children Chlorhexidine chronic rhinosinusitis chronic spontaneous urticaria Chronic Urticaria COVID-19 cytokine depression diagnosis drug allergy Drug hypersensitivity efficacy Epidemiology food allergy Food hypersensitivity house dust mite IgE Immunotherapy obstructive sleep apnea Omalizumab prevalence primary immunodeficiency Quality of life Questionnaire Reliability risk factor risk factors safety SARS-CoV-2 Sensitization Severe asthma Skin prick test Specific IgE Thai treatment urticaria vaccine Vitamin D
Asian Pacific Journal of Allergy and Immunology

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