Analysis of daily aspirin intake on platelet-associated factors and aggregation in nonsteroidal anti-inflammatory drugexacerbated respiratory disease: A cross-sectional study

Nonsteroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD) is a clinical syndrome characterized by chronic rhinosinusitis with nasal polyposis (CRSwNP), adult-onset asthma and hypersensitivity to NSAIDs. Long-term aspirin treatment after desensitization (ATAD) is used for clinical improvement in N-ERD patients. However, information on the potential effect of ATAD on the platelet-neutrophil aggregates (PNA) level in N-ERD patients is highly limited.
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Effect of budesonide nasal irrigationon Hypothalamic-Pituitary-Adrenal Axis in patientswith chronic rhinosinusitis post endoscopic sinus surgery: A prospective study

Corticosteroids added to high volume saline nasal irrigation have been introduced as a more effective method of delivering corticosteroids to the sinuses than nasal sprays. However, information regarding the effect of this intervention on the hypothalamic-pituitary-adrenal (HPA) axis is still limited.
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Denatonium benzoate promotes IgE-mediated mast celldegranulation and ovalbumin-induced allergic diarrheain BALB/c mice

Denatonium benzoate (DB), one of the most bitter compounds known to man, is used for alcohol denaturation. Some reports have demonstrated that asthmatic symptoms are associated with DB exposure, but the possible links between DB and immunoglobulin E (IgE)-mediated allergy susceptibility have not yet been examined.
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Cost-effectiveness of salbutamol via metered-dose inhaler with spacers versus nebulizers in childrenwith asthma exacerbation in middle income country

Previous studies have demonstrated that salbutamol administration via metered-dose inhaler with spacer (MDI-S) is as effective as using a jet nebulizer (NEB) for treating children experiencing asthma exacerbation. However, a paucity of research focuses on the direct medical costs associated with each mode of salbutamol administration for asthma exacerbation.
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Risk of allergic diseases in age-related macular degeneration: A nationwide cohort study in South Korea

Premorbid allergic diseases are linked with the development of age-related macular degeneration (AMD), however, the risk of allergic diseases among patients with AMD is largely unknown. Objective: To evaluate the association between AMD with or without visual disability (VD) and the risk of allergic diseases.
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Understanding the uncommon: Insights into thymoma associated immunodeficiency

Thymoma-associated immunodeficiency (TAI) is a rare, acquired adult-onset immunodeficiency. It includes the classic form of Good syndrome (GS), characterized by thymoma and hypogammaglobulinemia, as well as a non-classic form of GS. This condition leads to specific or combined deficiencies in both B- and T-cells, causing considerable morbidity and mortality, although the underlying immunopathology is still not well understood.
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Dysbiosis involving methionine and PPAR-γ pathwaysis associated with early onset atopic dermatitis and food allergy

Atopic dermatitis (AD) and food allergy (FA) often originate early in life. Gut microbiota interactions with the host immune system influence allergy development, yet the distinct gut microbiome and functional profiles in individuals with AD, FA, or both AD+FA remain underexplored.
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