Case Report – Page 2 – Asian Pacific Journal of Allergy and Immunology

March 15, 2021

A case report of allergic bronchopulmonary mycosis caused by Alternaria alternata in colonization of Aspergillus

Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disease caused by a complex hypersensitivity reaction to colonization of the airways with various fungi. ABPA caused by Alternaria alternata, other than Aspergillus spp., is named Allergic bronchopulmonary mycosis (ABPM).

ABPM, Allergic bronchopulmonary, Alternaria alternate, Asthma, Specific IgE

March 15, 2021

A case with Crohn’s disease-associated spondyloarthritis exhibiting enhanced pro-inflammatory cytokine responses to Toll-like receptor ligands

Despite the high incidence of spondyloarthritis (SpA) as an extra-intestinal manifestation of Crohn’s disease (CD), the immunopathogenesis of CD-associated SpA remains largely unknown.

Crohn’s disease, intestinal microflora, Pro-inflammatory Cytokines, spondyloarthritis, Toll-like receptor

January 30, 2021

A unique profile of serum cytokines in type 1 autoimmune pancreatitis and chronic rhinosinusitis

Type 1 autoimmune pancreatitis (AIP) is a pancreatic manifestation of IgG4-related disease (IgG4-RD). Although AIP and IgG4-RD are characterized by multiple organ involvement including salivary glands, lung, and kidney, co-occurrence of chronic rhinosinusitis (CRS) and AIP/IgG4-RD has been poorly defined.

chronic rhinosinusitis, cytokine, IgG4-related disease, IL-33, plasmacytoid dendritic cell (pDC), steroid, type 1 autoimmune pancreatitis

January 30, 2021

Perioperative anaphylaxis to chlorhexidine: Crucial role of in-vitro testing

Chlorhexidine is a synthetic biguanide with a broad antibacterial activity and has become an important cause of perioperative anaphylaxis.

basophil activation test, Chlorhexidine, drug allergy, perioperative anaphylaxis, tryptase

December 20, 2020

Immediate allergic reaction to thiocolchicoside confirmed by skin testing and basophil activation test: A case report and literature review

Thiocolchicoside is a muscle relaxant, anti-inflammatory, and analgesic. Administered orally, intramuscularly, or topically, this drug is used in the symptomatic treatment of muscular spasms and rheumatologic disorders. Despite its extensive use, thiocolchicoside is a very rare sensitizer.

basophil activation test, CD63+ basophils, central muscle relaxant, Drug hypersensitivity, immediate allergic reaction, Thiocolchicoside

December 2, 2020

Novel variants in CIITA caused type II bare lymphocyte syndrome: A case report

Type II bare lymphocyte syndrome (BLS II) group A is a rare primary severe immunodeficiency caused by defects in CIITA, one of genes encoding transcriptional regulatory factors for MHC II molecules.

CIITA gene, genetic disorder, MHC II, novel mutations, Type II bare lymphocyte syndrome

May 25, 2020

Epoetin-alfa induced pruritic maculopapular eruption: Case report and literature review

Erythropoiesis-stimulating agents (ESA) are commonly used in clinical practice to improve anaemia. Despite a number of patients successfully treated without adverse events, the complications have been previously reported.

Anaphylaxis, Drug eruptions, Drug hypersensitivity, Epoetin hypersensitivity, Erythropoietin

February 14, 2020

Corticosteroid-induced drug reaction with eosinophilia and systematic symptoms successfully treated with a tumor necrosis factor alpha inhibitor

Despite recent advances in the treatment of drug reaction with eosinophilia and systemic symptoms (DRESS), the mainstay of treatment involves discontinuing the culprit drugs and administering topical or systemic corticosteroid.

Drug Eruption, Drug Hypersensitivity Syndrome, Etanercept, Steroids, Tumor Necrosis Factor-alpha

January 29, 2020

Enzyme replacement therapy desensitization in a child with infantile onset Pompe disease

Enzyme replacement therapy significantly reduces morbidity and mortality in patients with Pompe disease. Development of hypersensitivity reactions to enzyme replacement therapy is common and can adversely affect disease outcomes when treatment is halted or delayed.

alglucosidase alfa, Desensitisation, Enzyme replacement, hypersensitivity, Pompe disease

December 16, 2019

Nonspecific interstitial pneumonia in refractory systemic juvenile idiopathic arthritis responded to tocilizumab treatment

Nonspecific interstitial pneumonia (NSIP) is a rare pulmonary complication in systemic juvenile idiopathic arthritis (SJIA).

interleukin-6, macrophage activation syndrome, nonspecific interstitial pneumonia, refractory systemic juvenile idiopathic arthritis, tocilizumab